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Supplement High Grade ACP105 Capsuels for Bodybuilding

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Supplement High Grade ACP105 Capsuels for Bodybuilding

ACP105 Capsuels-OASIS

Product name ACP-105 Capsuels
Chemical name ACP105
Category SARM
Storage at 20ºC 2 years

ACP105 Capsuels-OASIS

Description:

ACP-105 is a SARM (selective androgen receptor modulator) that helps people with degenerative bone disorders and provides support to athletes that are looking for increased muscle growth and better endurance. It has been frequently seen in the bodybuilding world where individuals report an increase in strength, quick gains in lean muscle mass, and maximized endurance.


Selective androgen receptor modulators (SARMS) have anabolic properties but have fewer side effects than anabolic androgen steroids. Their use is banned in both equestrian and human sports, and several cases of SARMS sightings have been reported in recent years. The objective of this study was to investigate the SARM ACP-105 (2-chloro-4 -[(3-endol) -3-hydroxy-3-methyl-8-azabicyclic [3.2.1] OCT-8-yl] -3-methylbenzonitrile) to find an analytical target for doping control. Oral administration of ACP-105 was performed in horses where blood and urine samples were collected over a period of 96 hours. In vivo samples were compared with five exoincubation models containing human and equine Caenorhabditis elegans, microsomes and S9 orders. TM Orbitrap TM mass spectrometry (UHPLC-HRMS). A total of 21 metabolites were identified in vivo, among which several new glucuronidates were detected in plasma and urine. Hydroxylated metabolites are dominant in hydrolyzed urine. In vitro models produced several biotransformation products, including many monohydroxylated metabolites that were consistent with in vivo results. A proposed analytical objective for control of horse doping in plasma is the net loss of two hydrogen dihydroxy metabolites. In urine, the recommended targets are two monohydroxylated metabolites hydrolyzed by β-glucuronidase, which were selected due to the extended detection time and availability of reference materials in an in vitro model.

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