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Hot Sales 99% Pure Piperaquine Phosphate

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Hot Sales 99% Pure Piperaquine Phosphate Piperaquine Phosphate-OASIS

Product Piperaquine Phosphate
Resource
Natural
Grade Medical grade
Purity 99%

What is Piperaquine Phosphate

In embryofetal studies in rat and rabbit Piperaquine phosphate (PQP) was not teratogenic at the maximal tolerated dose, even in presence of fetal exposure. In peri- post-natal study in rat, PQP did not interfere with the course of delivery at the dose of 5 mg/kg/day (treatment Gestation Day(GD)6-Lactation Day(LD)21) as well as up to the dose of 20 mg/kg/day (treatment GD6-17 and LD1-21). PQP at the dose of 80 mg/kg, induced prolonged gestation, dystocic delivery and increase perinatal mortality both with interruption of treatment (GD6 to GD17 and LD1-21) and with continuous dosing (GD19-LD21). 


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Function

PQP did not interfere with lactation and pup growth and development, in presence of clear exposure during suckling period, irrespective of the dose and treatment schedules. It was not possible to identify the mechanism leading to the delivery delay. In a comparative study using other antimalarials, only Mefloquine gave similar findings to PQP.


Specification

Items

Standards

Results

Physical Analysis



Description

White Powder Complies

Assay

99%(HPLC) 99.2%

Mesh Size

100 % pass 80 mesh Complies

Ash

≤ 5.0% 2.85%
Loss on Drying ≤ 5.0% 2.85%
Chemical Analysis

Heavy Metal ≤ 10.0 mg/kg Complies
Pb ≤ 2.0 mg/kg Complies
As ≤ 1.0 mg/kg Complies
Hg ≤ 0.1 mg/kg Complies
Microbiological Analysis

Residue of Pesticide Negative Negative
Total Plate Count ≤ 1000cfu/g Complies
Yeast&Mold ≤ 100cfu/g Complies
E.coil Negative Negative
Salmonella Negative Negative


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