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Chinese price hot sale high purity Letrozole powder CAS 112809-51-5

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Chinese price hot sale high purity Letrozole powder CAS 112809-51-5


Letrozole powder -OASIS


Letrozole - Names and Identifiers


Product Name: Letrozole

CAS Number: 112809-51-5
Indication:
For the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer. Also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.


Letrozole powder -oasis best Letrozole powder -OASIS
Mode of Action:

Letrozole is a nonsteroidal competitive inhibitor of the aromatase enzyme system; it inhibits the conversion of androgens to estrogens. In adult nontumor- and tumorbearing female animals, letrozole is as effective as ovariectomy in reducing uterine weight, elevating serum Leuteinizing hormone (LH), and causing the regression of estrogen-dependent tumors. In contrast to ovariectomy, treatment with letrozole does not lead to an increase in serum (folicile stimulating hormone (FSH). Letrozole selectively inhibits gonadal steroidogenesis but has no significant effect on adrenal mineralocorticoid or glucocorticoid synthesis.


Pharmacodynamics:

Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence of the breast tumor tissue.

Metabolism:

Primarily hepatic via CYP3A4 and CYP2A6. Letrozole inhibits the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues. It is metabolized slowly to an inactive metabolite whose glucuronide conjugate is excreted renally, representing the major clearance pathway.


Company introduction

Letrozole powder company -oasis

Shaanxi Oasis Bio-Tech Co., Ltd. is located Chanba Technology Park, Xi'an City, Shannxi Province, China 


It is a biotechnology enterprise engaged in the research, development, production and sales Sarms ,steroids peptides products and API, The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.The company has been adhering to the basic principles of "

Quality determines success , integrity determines the future" to serve customers!


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Q1: Can i get some samples? 

A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments? 

A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union 

or Paypal or Escrow.

Q3: How to confirm the Product Quality before placing orders? 

A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 


You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q4:What's your MOQ? 

A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Q5: How about delivery leadtime? 

A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6:Is there a discount? 

A:Different quantity has different discount.

Q7: How do you treat quality complaint? 

A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, 


we will send you free goods for replacement or refund your loss

  


Shaanxi Oasis Tech Co.,Ltd is a powerful manufacturer in the production and sales of SARMS ,steroids ,peptides and API products

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