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Product Nolvadex 20MG
Other name Tamoxifen
Application Muscle Building


Description

Tamoxifen, also known as tamoxifen citrate, is sold as Nolvadex®. It is a selective estrogen receptor modulator (SERM). This drug works by interfering with certain activities of estrogen, which mimics the effects of other estrogens. Tamoxifen is used to treat some types of breast and ovarian cancers. Researchers are currently comparing tamoxifen with raloxifene (another SERM) for their role in reducing breast cancer in high-risk groups.

[Pharmacological Mechanism of Action] This drug is a competitive antagonist of estradiol, which binds to estrogen receptors in breast cells and does not stimulate transcription or acts weakly. The drug - receptor complex is difficult to dissociate, and the circulation of the tissue receptor is also one of the mechanisms of action. Tamoxifen upregulates the production of transforming growth factor β, which is associated with the development of malignancy. It also has a specific inhibitory effect on protein kinase C. All of these effects have inhibitory effects on tumor cells that rely on estrogen to continue to grow. It is used for the treatment of progressive breast cancer after menopause. The effects of tamoxifen on plasma lipid metabolism, endometrium and bone were estrogenic but not antagonistic. The anti-osteoporosis effect of tamoxifen may also be related to the upregulation of transforming growth factor β, which controls the balance between osteoblasts and osteoclasts.



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Function

Tamoxifen is a potent and popular selective estrogen receptor modulator (SERM), and it was developed in 1961, and it was developed to treat breast cancer as well as to prevent breast cancer, and it was also found to be useful in steroid use as an anti-female drug. It acts as an estrogen in some tissues while blocking the action of estrogen in others. Although it is often seen circulating, it is not a steroid, and steroid users add tamoxifen to the circulation to prevent the side effects of the oergism reaction. And tamoxifen is often used in post-cycle recovery programs (PCT), which is its most valuable application

Tamoxifen is a selective estrogen receptor modulator. Tamoxifen works by replacing estrogen and binding to estrogen receptors. This combination prevents estrogen from working in certain parts of the body, and by doing so can minimize the risk of developing male breasts. (Testosterone, Vigorous tonic, Baodanone, etc., can cause the estradiation reaction.)

As an anti-female, liver tamoxifen acts like the female hormone oestrogen, which allows it to help users maintain healthy cholesterol levels. This is an attribute bonus, especially for steroid users, since many steroids have a negative effect on cholesterol levels in the body.

It is mainly used as an anti-estradiol, but tamoxifen has a strong testosterone stimulating effect. It prevents negative feedback in the hypothalamus and pituitary gland caused by estrogen. This stimulation increases the production of follicle stimulating hormone (FSH) and progesterone (LH), which are essential for natural testosterone production. Without LH and FSH (emphasis on LH), there is no testosterone production. 


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